The Chromosome 7 Annotation Project
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Chromosome 7 Clinical table -- LOSS OF HETEROZYGOSITY (Malignant)

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# Unique IDKaryotypePhenotypeCytogenetic Break FromCytogenetic Break ToMolecular Breakpoint #1Molecular Breakpoint #2Pubmed IDPatient ID          Comments          
1 9690521_GOS44_1 LOH(7) Wilms tumor p22 p15 D7S664/ 116XH6 GDB:1317612/ D7S638 9690521, 12461744 GOS 44 LOH on both 7p Edit
2 2842036_GOS231_2 4?, XY, t(7;11)(q32;p15) [1 cell], del(13)(q14q22) [2/10 cells], +18 [30%] Wilms tumor p21-22 p14-21 D7S517/ D7S507 D7S673/ D7S485 2842036, 9690521 GOS 231   Edit
3 9815935_T26_2 LOH(7) prostate cancer p15.2   D7S435   9815935 T26   Edit
4 9815935_T47 LOH(7p) prostate cancer p15.2   D7S435   9815935 T47 no 7q alterations Edit
5 7664288_44 LOH(7) prostate cancer p14 q31 D7S484/ D7S510 D7S523/ D7S486 7664288 44   Edit
6 7664288_19 LOH(7) prostate cancer         7664288 19   Edit
7 7664288_33 LOH(7) prostate cancer         7664288 33   Edit
8 7664288_51 LOH(7) prostate cancer         7664288 51   Edit
9 7664288_8 LOH(7) prostate cancer         7664288 8   Edit
10 7664288_12 LOH(7) prostate cancer         7664288 12   Edit
11 7664288_46 LOH(7) prostate cancer         7664288 46   Edit
12 7664288_6 LOH(7) prostate cancer   q31.3 D7S501/ D7S486 D7S522/ D7S480 7664288 6   Edit
13 10329610_S5 LOH(7) splenic marginal B-cell lymphoma     D7S471/ D7S2847 D7S487/ D7S514 10329610, 11830479 S5 [10329610], 5 [11830479]   Edit
14 7664288_26 LOH(7) prostate cancer pter p11.1     7664288 26   Edit
15 10646884_WT30 LOH(7) Wilms Tumour       D7S691/ D7S554 10646884 WT30   Edit
16 7954327_WT40 46, XX [LOH(7)] Wilms Tumour       D7S3023/ D7S691 7954327, 10646884 WT40   Edit
17 10646884_WT42 LOH(7) Wilms Tumour       D7S3023/ D7S554 10646884 WT42   Edit
18 12080476_32 LOH(7) primary head and neck squamous cell carcinoma pter qter     12080476 32   Edit
19 9892108_2 46, XX [LOH(7)] invasive epithelial ovarian carcinoma pter qter     9892108 2   Edit
20 12080476_8 LOH(7) primary head and neck squamous cell carcinoma   q31.31 D7S1799/ D7S486 D7S486/ D7S522 12080476 8   Edit
21 12080476_23 LOH(7) primary head and neck squamous cell carcinoma   q31.3 D7S1799/ D7S486 D7S486/ D7S643 12080476 23   Edit
22 12080476_26 LOH(7) primary head and neck squamous cell carcinoma   q31.32 D7S1799/ D7S486 D7S643/ D7S480 12080476 26   Edit
23 12080476_37_1 LOH(7) primary head and neck squamous cell carcinoma   q31 D7S1799/ D7S525 D7S525/ D7S522 12080476 37   Edit
24 12080476_39 LOH(7) primary head and neck squamous cell carcinoma   q31.3 D7S1799/ D7S486 D7S486/ D7S480 12080476 39   Edit
25 12080476_41 LOH(7) primary head and neck squamous cell carcinoma   q31 D7S1799/ D7S525 D7S525/ D7S522 12080476 41   Edit
26 12080476_45_1 LOH(7) primary head and neck squamous cell carcinoma   q31.31 D7S1799/ D7S486 D7S486/ D7S522 12080476 45   Edit
27 12080476_47 LOH(7) primary head and neck squamous cell carcinoma     D7S1799/ D7S486   12080476 47   Edit
28 12080476_48 LOH(7) primary head and neck squamous cell carcinoma   q31.32   D7S643/ D7S480 12080476 48   Edit
29 9892108_143 46, XX [LOH(7)] invasive epithelial ovarian carcinoma     D7S518/ 7G14   9892108 143 primary tumor and metastatic tissue Edit
30 9892108_216_1 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31 D7S518/ D7S523 D7S523/ D7S486 9892108 216   Edit
31 9892108_8 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31.31 D7S518/ D7S523 7G4/ 7G2 9892108 8   Edit
32 9892108_155_1 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31.31   D7S522/ 7G4 9892108 155   Edit
33 9892108_45_1 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31.31 D7S518/ D7S486 7G14/ 7G4 9892108 45   Edit
34 9892108_179_1 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31.31 D7S518/ D7S486 D7S486/ 7G14 9892108 179   Edit
35 9892108_150 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31.31 D7S518/ D7S486 D7S486/ D7S522 9892108 150   Edit
36 9892108_146 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31.31   D7S486/ 7G15 9892108 146   Edit
37 9892108_30_2 46, XX [LOH(7)] invasive epithelial ovarian carcinoma     D7S487/ D7S500   9892108 30   Edit
38 9892108_134_1 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31   D7S523/ D7S486 9892108 134   Edit
39 9892108_177 46, XX [LOH(7)] invasive epithelial ovarian carcinoma   q31 D7S518/ D7S523 D7S523/ 7G14 9892108 177   Edit
40 9892108_94 46, XX [LOH(7)] invasive epithelial ovarian carcinoma       D7S518/ D7S523 9892108 94   Edit
41 9892108_1 46, XX [LOH(7)] invasive epithelial ovarian carcinoma       D7S518/ D7S523 9892108 1   Edit
42 9892108_5_2 46, XX [LOH(7)] invasive epithelial ovarian carcinoma     D7S480/ D7S500   9892108 5   Edit
43 12681970_2 46, XX, -20, +mar [LOH(7)] acute myeloid leukemia     D7S658/ D7S2459 D7S486/ D7S530 12681970 2   Edit
44 12681970_5 46, XX, del(11)(q23) [LOH(7)] acute myeloid leukemia   q22.1 D7S657/ D7S515 D7S515/ D7S666 12681970 5   Edit
45 12681970_7 47, XY, +8, inv(16)(p13q22) [LOH(7)] acute myeloid leukemia   q22.1 D7S657/ D7S515 D7S515/ D7S666 12681970 7   Edit
46 12681970_8 46, XX, t(6;9)(p23;q34) [LOH(7)] acute myeloid leukemia   q22.1 D7S657/ D7S515 D7S515/ D7S666 12681970 8   Edit
47 12681970_9 LOH(7) acute myeloid leukemia   q33 D7S530/ D7S640 D7S640/ D7S631 12681970 9 hyperdiploidy Edit
48 12681970_12 46, XY, t(1;3)(p32;q11) [LOH(7)] pro T-cell acute lymphoid leukemia     D7S640/ D7S1826   12681970 12   Edit
49 12681970_13 46, XY [LOH(7)] common-acute lymphoid leukemia   q21.2   D7S630/ D7S492 12681970 13   Edit
50 12681970_14 47, XX, +18 [LOH(7)] acute lymphoid leukemia     D7S657/ D7S515   12681970 14   Edit
51 11489466_29_1 LOH(7) myeloproliferative disease   q31.1   D7S692/ D7S525 11489466 29   Edit
52 10071086_12 LOH(7) acute myeloid leukemia     D7S510/ D7S523   10071086 12   Edit
53 10071086_16 LOH(7) acute myeloid leukemia       D7S487/ D7S500 10071086 16   Edit
54 10071086_5_1 LOH(7) acute myeloid leukemia       D7S527/ D7S518 10071086 5   Edit
55 10071086_5_2 LOH(7) acute myeloid leukemia     D7S518/ D7S677 D7S522/ D7S500 10071086 5   Edit
56 10071086_7 LOH(7) acute myeloid leukemia     D7S500/ D7S498 D7S505/ D7S550 10071086 7   Edit
57 9205105_336 LOH(7) invasive epithelial ovarian carcinoma pter qter     9205105 336   Edit
58 9205105_412 LOH(7) invasive epithelial ovarian carcinoma pter qter     9205105 412   Edit
59 9205105_ES-9 LOH(7) invasive epithelial ovarian carcinoma   q31.32   D7S643/ D7S480 9205105 ES-9   Edit
60 9205105_ES-3_1 LOH(7) invasive epithelial ovarian carcinoma       D7S2554/ D7S655 9205105 ES-3   Edit
61 9205105_B27_1 LOH(7) invasive epithelial ovarian carcinoma       D7S2554/ D7S486 9205105 B27   Edit
62 9205105_357_1 LOH(7) invasive epithelial ovarian carcinoma   q31.31 D7S687/ D7S486 D7S633/ D7S655 9205105 357   Edit
63 9205105_377_1 LOH(7) invasive epithelial ovarian carcinoma   q31.31 D7S2502/ D7S486 D7S486/ D7S522 9205105 377   Edit
64 9205105_443_1 LOH(7) invasive epithelial ovarian carcinoma   q31.31   D7S522/ D7S633 9205105 443   Edit
65 9205105_489 LOH(7) invasive epithelial ovarian carcinoma   q31.31 D7S687/ D7S486 D7S486/ D7S677 9205105 489   Edit
66 9205105_528_1 LOH(7) invasive epithelial ovarian carcinoma   q31.31 D7S523/ D7S522 D7S522/ D7S633 9205105 528   Edit
67 9690521_GOS44_2 LOH(7) Wilms tumor     D7S517/ D7S507   9690521, 12461744 GOS 44 LOH on both 7p; Molecular 2 is bounded by D7S507/ D7S664 Edit
68 9690521_GOS96 LOH(7) Wilms tumor   p21.2   D7S507/ D7S503 9690521 GOS 96   Edit
69 9690521_GOS146 LOH(7) Wilms tumor       D7S517/ D7S503 9690521 GOS 146   Edit
70 8938443_3 50, XY [LOH(7)] Wilms tumor     D7S526/ D7S484   8938443 3 (W13)   Edit
71 9135988_3 LOH(7) ovarian cancer     D7S510/ D7S527   9135988 3   Edit
72 9135988_17 LOH(7) ovarian cancer     D7S510/ D7S527   9135988 17   Edit
73 9135988_19 LOH(7) ovarian cancer     D7S510/ D7S518   9135988 19   Edit
74 9135988_5 LOH(7) ovarian cancer     D7S518/ D7S523 D7S523/ D7S486 9135988 5   Edit
75 9135988_12 LOH(7) ovarian cancer     D7S527/ D7S486 D7S486/ D7S480 9135988 12   Edit
76 9135988_14 LOH(7) ovarian cancer     D7S518/ D7S523 D7S480/ D7S487 9135988 14   Edit
77 9135988_15_1 LOH(7) ovarian cancer     D7S527/ D7S486 D7S522/ D7S655 9135988 15   Edit
78 9135988_15_2 LOH(7) ovarian cancer     D7S522/ D7S655   9135988 15   Edit
79 9135988_16_1 LOH(7) ovarian cancer       D7S517/ D7S493 9135988 16   Edit
80 9135988_16_2 LOH(7) ovarian cancer     D7S510/ D7S523 D7S500/ D7S498 9135988 16   Edit
81 9135988_18 LOH(7) ovarian cancer     D7S510/ D7S527 D7S480/ D7S500 9135988 18   Edit
82 9135988_22 LOH(7) ovarian cancer     D7S523/ D7S655   9135988 22   Edit
83 9520444_19 monosomy 7 [LOH(7)] preleukemic myelodysplastic syndrome, acute myeloid leukemia pter qter D7S2545/ D7S692   9520444 19 q22 markers (D7S2446, D7S2545) are retained Edit
84 8934547_005 LOH(7q) breast cancer       MetH$/ D7S504 8934547 tumor 005   Edit
85 8934547_009 LOH(7q) breast cancer       D7S643/ D7S483 8934547 tumor 009   Edit
86 8934547_015 LOH(7q) breast cancer     D7S506/ D7S461 D7S643/ D7S500 8934547 tumor 015   Edit
87 8934547_025 LOH(7q) breast cancer     D7S506/ D7S461 D7S655/ D7S500 8934547 tumor 025   Edit
88 8934547_074 LOH(7q) breast cancer     D7S506/ D7S471 D7S643/ D7S504 8934547 tumor 074   Edit
89 8934547_540 LOH(7q) breast cancer     D7S506/ D7S2554 D7S655/ D7S504 8934547 tumor 540   Edit
90 8934547_2632 LOH(7q) breast cancer     D7S506/ D7S523 D7S504/ D7S500 8934547 tumor 2632   Edit
91 7960231_1 LOH(7q) gastric carcinoma         7960231 1   Edit
92 7960231_20 LOH(7q) gastric carcinoma     D7S64/ D7S22$   7960231 20   Edit
93 7960231_25 LOH(7q) gastric carcinoma         7960231 25   Edit
94 7960231_27 LOH(7q) gastric carcinoma     D7S63/ D7S95   7960231 27   Edit
95 7960231_31 LOH(7q) gastric carcinoma     MET/ D7S95 D7S95/ D7S22 7960231 31   Edit
96 7960231_32 LOH(7q) gastric carcinoma       D7S63$/ D7S22$ 7960231 32   Edit
97 7960231_33 LOH(7q) gastric carcinoma         7960231 33   Edit
98 7960231_35 LOH(7q) gastric carcinoma     MET$/ D7S63$ D7S63$/ D7S22$ 7960231 35   Edit
99 7960231_41 LOH(7q) gastric carcinoma     D7S64/ MET   7960231 41   Edit
100 7960231_43 LOH(7q) gastric carcinoma     D7S63/ D7S95   7960231 43   Edit
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